86Y Based PET Radiopharmaceuticals: Radiochemistry and Biological Applications
نویسندگان
چکیده
منابع مشابه
PET tracers and radiochemistry.
This paper provides a brief review of the radiochemistry of radiopharmaceuticals used in positron emission tomography (PET). It includes some history of PET, the basic formation of radionuclides in a cyclotron target, the processing of the precursor molecules into a useful PET radiotracer and the clinical significance and outlook for PET radiotracers. This review is based on a series of recent ...
متن کاملPET Radiochemistry and Radiopharmacy
References .......................................................................... 27 Abstract The vast majority of PET radiopharmaceuticals today are cyclotron produced. Carbon-11 (C), Nitrogen-13 (N), Oxygen-15 (O) products are created for in-house use only due to their short half-lives. The longer half-life of Fluorine-18 means that F-labeled PET radiotracers can be widely distributed. Pr...
متن کاملPET Radiopharmaceuticals
PET (positron emission tomography) is a powerful imaging technique that can provide quantitative information on the distribution of positron emitter labeled radiopharmaceuticals (PET radiopharmaceuticals) in the body. Positrons (ß+) are positively charged beta particles. They are emitted when the atom is proton rich. A positron has only a transient existence. After losing all of its kinetic ene...
متن کاملPET Radiopharmaceuticals
PET (positron emission tomography) is a powerful imaging technique that can provide quantitative information on the distribution of positron emitter labeled radiopharmaceuticals (PET radiopharmaceuticals) in the body. Positrons (ß+) are positively charged beta particles. They are emitted when the atom is proton rich. A positron has only a transient existence. After losing all of its kinetic ene...
متن کاملRadiochemistry on chip: towards dose-on-demand synthesis of PET radiopharmaceuticals.
We have developed an integrated microfluidic platform for producing 2-[(18)F]-fluoro-2-deoxy-D-glucose ((18)F-FDG) in continuous flow from a single bolus of radioactive isotope solution, with constant product yields achieved throughout the operation that were comparable to those reported for commercially available vessel-based synthesisers (40-80%). The system would allow researchers to obtain ...
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ژورنال
عنوان ژورنال: Medicinal Chemistry
سال: 2011
ISSN: 1573-4064
DOI: 10.2174/157340611796799249